Insulin-like activity and immunoreactive insulin content of gel-filtered protein fractions of bovine serum

Distribution of syphilitic antibodies in gel-filtered serum fractions.

Sera from patients with primary syphilis have been fractionated by numerous investigators in order to explore the serological reactivity of the various classes of immunoglobulin. The methods applied have been the following: Electrophoresis (Laurell, 1955; Laurell and Lindau, 1958; Portnoy, Julian, Smith and Harris, 1963); Density gradient ultracentrifugation (Aho, 1967; Davis, Moore, Kabat, and...

Nonsuppressible insulin-like activity of human serum.

Effect of Six Months of Aerobic Exercise on Serum Levels of Insulin, Growth Hormone and Insulin-Like Growth Hormone 1 in Sedentary Obese Women

ABSTRACT            Background and Objectives: Inactivity, obesity and hormone disorders can lead to various diseases in obese and non-athletic individuals. The objective of this study was to investigate effects of six months of aerobic exercise on serum levels of insulin, growth hormone (GH) and insulin-like growth hormone 1 (IGF-1) in sedent...

Apparent inhibition of liver insulinase activity by serum and serum fractions containing insulin-binding antibody.

A number of anti-insulin factors present in the serum of insulin-resistant subjects has been reported. Lowell (1) presented evidence for both insulin-neutralizing and insulin-sensitizing antibodies. De Fillipis and lannaccone (2) and Colwell and Weiger (3) employing salting out methods and Sehon, Kaye, McGarry, and Rose (4) using starch electrophoresis have reported that insulin-neutralizing ac...

The Insulin-like Growth Factor-1 (G>A) and 5,10-methylenetetrahydrofolate Reductase (C677T) Gene Variants and the Serum Levels of Insulin-like Growth Factor-1, Insulin, and Homeostasis Model Assessment in Patients with Acne Vulgaris

Background & Objective: To find an association between gene variants of insulin-like growth factor-1 (IGF-1) and 5,10-methylenetetrahydrofolate reductase (MTHFR) with the risk of acne vulgaris (AV). Methods: In a case-control study, we investigated 150 AV patients and 148 healthy individuals (aged 18-25 years) for the IGF-1 G>A and MTHFR C677T polymorphis...